Does clinical trial subject selection restrict the ability to generalize use and cost of health services to “real life” subjects?

Title : Does clinical trial subject selection restrict the ability to generalize use and cost of health services to real life subjects?

Source : PubMed
ID : 12701935
Authors : Kennedy WA, Laurier C, Malo JL, Ghezzo H, L Archevêque J, Contandriopoulos AP.
Year : 2003
Disease Category : Respiratory diseases
Focused Population : Not Specified
Priori/Posteriori : Posteriori
Single-study Generalibility? : Single
Score/Non-Score : Non-score
Tutorial/Method : NHANES_T2D
Compared general demographic and patient characteristics : Yes
Compared disease-specific clinical characteristics : Yes
Compared adverse events : No
Compared outcomes/treatment effect (including survival) : No
Trial participants v.s. non-participants (excluded by the trial, or eligible but non-randomized) : Yes
Real-world data sources : trial participants
Target Population Data Type Levels : Trial
Test characteristics between two groups? : Yes
Linear regression : Yes
Logistic regression : Yes