Generalizability of clinical trials of advanced melanoma in the real-world, population-based setting

Title : Generalizability of clinical trials of advanced melanoma in the real-world, population-based setting

Source : CINAHL
ID : 29915956
Authors : Sam, Davis; Gresham, Gillian; Abdel-Rahman, Omar; Cheung, Winson Y
Year : 2018
Disease Category : Cancer
Focused Population : Not Specified
Priori/Posteriori : Priori
Single-study Generalibility? : Multiple
Score/Non-Score : Non-score
Tutorial/Method : Based on eligibility criteria as described in registration trials of vemurafenib (Vem) and ipilimumab (Ipi), we classified patients into trial-eligible and ineligible and those treated and untreated with these agents
Compared general demographic and patient characteristics : No
Compared disease-specific clinical characteristics : Yes
Compared adverse events : No
Compared outcomes/treatment effect (including survival) : No
Eligible patients (by applying criteria) vs. ineliglble patients (by applying criteria) : Yes
Real-world data sources : Patients referred to cancer centers in a large Canadian province
Target Population Data Type Levels : Regional