Generalizability of the FOURIER trial to routine clinical care: Do trial participants represent patients in everyday practice?

Title : Generalizability of the FOURIER trial to routine clinical care: Do trial participants represent patients in everyday practice?

Source : PubMed
ID : 30685675
Authors : Yao, Xiaoxi; Gersh, Bernard J.; Lopez-Jimenez, Francisco; Shah, Nilay D.; Noseworthy, Peter A
Year : 2018
Disease Category : Cardiovascular diseases
Focused Population : Elderly patients, Gender, Ethnicity
Priori/Posteriori : Both
Single-study Generalibility? : Single
Score/Non-Score : Non-score
Tutorial/Method : NHANES_T2D
Compared general demographic and patient characteristics : Yes
Compared disease-specific clinical characteristics : Yes
Compared adverse events : No
Compared outcomes/treatment effect (including survival) : Yes
Trial participants vs. eligible patients (by applying eligibility criteria on the patient data) : Yes
Eligible patients (by applying criteria) vs. ineliglble patients (by applying criteria) : Yes
Real-world data sources : adult patients with ASCVD in OptumLabs Data Warehouse (OLDW)
Target Population Data Type Levels : National