Has the symptom severity inclusion requirement narrowed the definition of major depressive disorder in antidepressant efficacy trials?

Title : Has the symptom severity inclusion requirement narrowed the definition of major depressive disorder in antidepressant efficacy trials?

Source : PubMed
ID : 28088058
Authors : Zimmerman, Mark; Walsh, Emily; Chelminski, Iwona; Dalrymple, Kristy
Year : 2017
Disease Category : Mental disorder
Focused Population : Not Specified
Priori/Posteriori : Priori
Single-study Generalibility? : Single
Score/Non-Score : Non-score
Tutorial/Method : Compared the distribution of DSM-IV MDD criteria scores in patients who scored at or above or below the 3 cutoff scores on the HAMD most commonly used for inclusion in an AET
Compared general demographic and patient characteristics : No
Compared disease-specific clinical characteristics : No
Compared adverse events : No
Compared outcomes/treatment effect (including survival) : No
Real-world data sources : The Rhode Island MIDAS project
Target Population Data Type Levels : Regional