The generalizability of antidepressant efficacy trials to routine psychiatric out-patient practice.

Title : The generalizability of antidepressant efficacy trials to routine psychiatric out-patient practice

Source : PsycINFO
ID : 21078225
Authors : van der Lem, R.; van der Wee, N. J. A.; van Veen, T.; Zitman, F. G
Year : 2011
Disease Category : Mental disorder
Focused Population : Not Specified
Priori/Posteriori : Priori
Single-study Generalibility? : Multiple
Score/Non-Score : Non-score
Tutorial/Method : Eligibility was assessed by stepwise application of commonly used exclusion criteria. Influence of eligibility on treatment outcome was investigated in a subsample of the 1653 patients who had at least one follow-up assessment (n = 626). Eligible and non-eligible patients were compared on proportion of response (50% reduction) and remission on MADRS
Compared general demographic and patient characteristics : No
Compared disease-specific clinical characteristics : No
Compared adverse events : No
Compared outcomes/treatment effect (including survival) : Yes
Eligible patients (by applying criteria) vs. ineliglble patients (by applying criteria) : Yes
Real-world data sources : Hospital data
Target Population Data Type Levels : Hospital